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KMID : 0389420150230040179
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Korean Journal of Stress Research
2015 Volume.23 No. 4 p.179 ~ p.185
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Plasma Homocysteine Concentraton according to the Depression and Degree of Stress
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임창욱:Lim Chang-Wook
문지현:Moon Ji-Hyun/김현주:Kim Hyeon-Ju/공미희:Kong Mi-Hee
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Abstract
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In this study, we investigated plasma homocysteine concentration according to the depression and degree of stress. The study subjects were 1,395 adults aged over 20 years who visited a health promotion center. Medical history was recorded through a self-reported questionnaire and physical examination was performed on all subjects. We measured plasma homocysteine by blood sampling after fasting over 8 hours. To determine depression, we used CES-D in the subjects below the age of 65 and GDS over the age of 65. The stress group is divided into three subgruoups by using BEPSI. We adjusted for all variables that affect the homocysteine. The homocysteine concentration was not associated with depression regardless age and sex. There was significant differentiation of plasma homocysteine concentration according the degree of stress in men, but no differentiation in Women. This study showed no relationship between depression and plasma homocysteine concentration. We found that men in high stress group had a tendency for higher plasma homocysteine concentration.
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KEYWORD
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Homocysteine, Depression, Stress
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